The pathophysiology of melasma remains elusive, but multiple factors have been implicated. The clinical and histological features of melasma in men are the same as those of melasma in women.
It is much more common in women during their reproductive years but about 10% of the cases do occur in men.
Melasma is the most common pigmentary disorder among Indians.
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The term, “chloasma” (from the Greek word, ‘ chloazein’ meaning ‘to be green’) is often used to describe melasma developing during pregnancy however, as the pigmentation never appears to be green, the term, “melasma” should be preferred.Īlthough melasma may affect any race, it is much more common in constitutionally darker skin types (skin types IV to VI) than in lighter skin types, and it may be more common in light brown skins, especially in people of East Asian, Southeast Asian, and Hispanic origin who live in areas of the world with intense solar ultraviolet exposure. The most common locations are the cheeks, upper lips, the chin, and the forehead, but other sun-exposed areas may also occasionally be involved. It presents as symmetric, hyperpigmented macules having irregular, serrated, and geographic borders. Melasma (from the Greek word, ‘ melas’ meaning black) is a common, acquired, circumscribed hypermelanosis of sun-exposed skin. Well-designed controlled clinical trials are needed to clarify their role in the routine management of melasma. The search for safer alternatives has given rise to the development of many newer agents, several of them from natural sources. Prolonged HQ usage may lead to untoward effects like depigmentation and exogenous ochronosis. The most popular combination consists of HQ, a topical steroid, and retinoic acid. Combination therapy is the preferred mode of treatment for the synergism and reduction of untoward effects. Topical medications modify various stages of melanogenesis, the most common mode of action being inhibition of the enzyme, tyrosinase. Besides HQ, other topical agents for which varying degrees of evidence for clinical efficacy exist include azelaic acid, kojic acid, retinoids, topical steroids, glycolic acid, mequinol, and arbutin. Multiple options for topical treatment are available, of which hydroquinone (HQ) is the most commonly prescribed agent. In addition to avoidance of aggravating factors like oral pills and ultraviolet exposure, topical therapy has remained the mainstay of treatment. The management of melasma is challenging and requires a long-term treatment plan. Be sure to keep your eyes peeled for Prime Day deals!ĭon't forget to follow Good Housekeeping on TikTok.Melasma is a common hypermelanotic disorder affecting the face that is associated with considerable psychological impacts. They are on sale for 33% off and would make a great gift for teens if you're planning to start your holiday shopping during Prime Day.Īhead, check out 33 quirky (and incredibly useful) TikTok Amazon finds for your home. And you might have noticed lots of people wearing cloud slides lately. The insanely viral butt-sculpting leggings are around 20% off (the exact discount depends on color and size), bringing them to under $20. 11 and 12, and some of the most popular products from TikTok are included in the sale. Lucky for us, Amazon is hosting a fall Prime Day on Oct. Amazon even launched a landing page dedicated to viral TikTok items, aptly named #FoundItOnAmazon.īy now, we're sure you've found some innovative products on TikTok, like the wall-cleaning mop that broke the internet to the adult-sized kiddie pool that's big enough to fit all your friends. The one-stop social media platform simultaneously repopularizes old songs and inspires dance crazes, but above it all, product recommendations and useful hacks dominate the app. Let's admit it: We spend a huge fraction of our screen time scrolling on TikTok. Each one boasts at least 500 reviews and a minimum 4-star rating from real, verified reviewers, so you can trust that you’re purchasing products that actually work, according to users and experts.
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